Analytical Ultracentrifugation Services

Nanolytics is a specialized analytical services provider with more than 20 years of experience in analytical ultracentrifugation. Our centrifuges are equipped with superior detection capabilities, e.g. increasing the sensitivity by a factor 5, or taking full spectra rather than fixed-wavelength absorbance, enhancing the characterization of your sample (4-dimensional 4D-AUC) and allowing for more flexibility in regard to the systems in question and their testing conditions.

Analytical Ultracentrifugation (AUC) is a versatile method with different experimental approaches – sedimentation velocity, equilibria, and density gradients are examples for different experimental techniques. Density variation (measurements in deuterated solvents) further expands the capabilities of these techniques. Our team is experienced and creative in designing AUC experiments for maximum benefit.

Analytical Ultracentrifugation (AUC) addresses a large set of hydrodynamic properties, allowing for in-depth characterization of particles and molecules in respect to their size, mass, density, and conformation. Analytical Ultracentrifugation is the only physical method capable of separating particles by their density, a property most useful for discriminating objects of similar mass and size. A large set of software tools, both developed in-house or by leading AUC scientists, is at hand to address different tasks and target properties. We are experienced in using these complex tools that require both insight and experience.

Rotor and cells
Rotor and cells

Nanolytics has been providing its services to a large number of major pharmaceutical companies, gathering knowledge and experience both in routine tasks and advanced, complex analyses. We provide continuity in regard to the personnel involved and integrate prior and gained knowledge into the further course of long-term projects. In close touch with our clients, we do not only perform and evaluate measurements – we interpret and explain the outcome, assisting you in getting the most out of our results.

Nanolytics provides quick response times. Typically, analyses are run within a few days upon sample receipt. Reports are compiled within a few more days.